Program
Morning sessions will be devoted to lectures given by experts in biology, biomechanics, nanotechnology, and relevant topics. In the afternoons, trainees will participate in four hands-on laboratory modules in different labs on campus. Each participant is required to present a poster of his/her current research (not necessarily related to cellular and molecular mechanics); you may find instructions for poster size and content online. A session for the trainees to interact with each other will also be organized.
Presentations
As presentations are provided to us, we will link them in the program below. All presentations will be provided in PDF format, which requires a program like Adobe Acrobat Reader or FoxIt Reader to be read.
Laboratory Modules
Participants Lab Group Assignment
- Molecular Biology Lab Module
- Cellular Biology Lab Module
- Micro- & Nano-Fabrication Lab Module
- Enabling Technology Lab Module
Note: All lectures will be at 1000 Micro and Nano Technology Laboratory.
Week 1
Day 1 – June 8
| Session Chair: Irfan Ahmad | |
| 8:30 - 9:00 | Opening Ceremony |
| Welcome to Illinois, Ilesanmi Adesida, Dean of Engineering | |
| Welcome to GEM4 Summer School, Jimmy Hsia, Organizing Committee Chair | |
| Introduction of THE TEAM, Jimmy Hsia | |
| About MNTL, Rashid Bashir, Director of MNTL | |
| About CNST, Irfan Ahmad, Associate Director of CNST | |
| About CCM, Taher Saif, Director of CCM | |
| GEM4 Summer School Logistics, Jimmy Hsia | |
| 9:00 - 9:50 | Fundamentals of cell and molecular biology - I Scott Siechen (Illinois) |
| 9:50 - 10:10 | Coffee break |
| 10:10 - 11:00 | Fundamentals of cell and molecular biology - II Scott Siechen (Illinois) |
| 11:00 - 11:50 | Basics of mechanics in connection with biological systems Jimmy Hsia (Illinois) |
| 12:00 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
Day 2 – June 9
| Session Chair: Brendan Harley | |
| 8:10 - 9:00 | Mechanotransduction at a distance in a living cell Ning Wang (Illinois) |
| 9:00 - 9:50 | Mechanics insights into the pathophysiology of human disease; Microfluidics approaches to studying human diseases Chwee Teck Lim (National U of Singapore) |
| 9:50 - 10:10 | Coffee break |
| 10:10 - 11:00 | Effects of mechanical stiffness and applied force on ligand-receptor binding kinetics at the cell-material interface Krytyn van Vliet (MIT) |
| 11:00 - 11:50 | Fundamentals of molecular dynamics and computational molecular nanomechanics Markus Buehler (MIT) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
Day 3 – June 10
| Session Chair: Taher Saif | |
| 8:10 - 9:00 | Mechanics and Bioengineering of Basement Membranes and Extracellular Matrix Raghu Kalluri (Harvard Medical School) |
| 9:00 - 9:50 | Inflammation in Human Disease and the Autodigestion Hypothesis Geert Schmid-Schonbein (UC - San Diego) |
| 9:50 - 10:10 | Coffee break |
| 10:10 - 11:00 | Engineering Digital Surfaces for Programming Cell Responses Ralph Kemkemer/Joachim Spatz (Max Planck Inst) |
| 11:00 - 11:50 | Fundamental Problems of Computational Biomechanics of Cardiovascular Flow Takami Yamaguchi (Tohoku U) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
| 6:00 - 8:00 | GEM4 Executive Committee Meeting |
Day 4 – June 11
| Session Chair: Peter Wang | |
| 9:00 - 9:50 | Review of Cellular Imaging Techniques Gang Bao (GaTech) |
| 9:50 - 10:10 | Summer School Picture Taking & Coffee break |
| 10:10 - 11:00 | Statistical mechanics of cell-cell and cell-matrix adhesions; Multi-scale approaches to study cellular adhesions Muhammad Zaman (UT-Austin) |
| 11:00 - 11:50 | Models and Experiments in Cytoskeletal Mechanics Roger Kamm (MIT) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
| 6:30 - 9:30 | Summer School Banquet (in conjuction with Biophotonics Summer School) Cash Bar - 6:30 Dinner - 7:00 Location: Chancellor Ballroom at I-Hotel |
Day 5 – June 12
| Session Chair: Yann Robert Chemla | |
| 9:00 - 9:50 | Cell microrheology: fundamentals and applications Denis Wirtz (Johns Hopkins U) |
| 9:50 - 10:40 | Next generation single molecule fluorescence technologies Taekjip Ha (Illinois) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | Intracellular Force Transduction Michael Sheetz (Columbia U) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 4:30 | Poster Session |
| 4:30 - 6:00 | Best Poster Award Announcement and Happy Hour |
Day 6 – June 13
| 8:30 am - 6:00 pm | Excursion: Chicago Follett's Book Store Bus Departs from Chicago for Champaign-Urbana at 7:00 PM |
Follet's bookstore, where the bus leaves for the trip to Chicago on Sautrday June 13 is just south of MNTL wher the lectures are located. (A) is MNTL while (B) is the bookstore on the following map.
Week 2
Day 1 – June 15
| Session Chair: Supriya Prasanth | |
| 9:00 - 9:50 | Microfluidic systems in neurobiology Martha Gillette (Illinois) |
| 9:50 - 10:40 | Probing Cellular Motility using Microfluidic Tools Daniel Irimia (Harvard Medical School) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | Migration of epithelial cells Paul Matsudaira (National U of Singapore) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
Day 2 – June 16
| Session Chair: Amy Wagoner-Johnson | |
| 9:00 - 9:50 | Small Scale Biomechanics Measurements Beth Pruitt (Stanford U) |
| 9:50 - 10:40 | Electro-mechanical Sensing of Biomolecules and Cells on a Chip Rashid Bashir (Illinois) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | FIONA: Super-'Resolution' Microscopy Paul Selvin (Illinois) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
Day 3 – June 17
| Session Chair: Timothy Fan | |
| 9:00 - 9:50 | Moving cells on chips, microfluidics, and clinical medicine Mehmet Toner (Harvard Medical School) |
| 9:50 - 10:40 | Mechanotransduction at cell-cell contacts Deborah Leckband (Illinois) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | Nanotechnology for Cellular and Molecular Manipulations Logan Liu (Illinois) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Lab Session M1 |
| 3:00 - 5:00 | Lab Session M2 |
Day 4 – June 18
| Session Chair: Hyun Joon Kong | |
| 9:00 - 9:50 | Live cell imaging in mechanobiology Peter Wang (Illinois) |
| 9:50 - 10:40 | Deciphering mechanical and chemical signals in the extracellular matrix Jean Schwarzbauer (Princeton U) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | Computational methods for understanding the dynamics of
interacting motor molecules in muscles Thomas Daniel (U Washington) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 2:30 | Special Session I: Research Idea Exchange (speed-dating style) |
| 2:30 - 3:00 | Discussion: Issues in Physical Sciences - Biology Collaboration Paul Janmey (U Penn) |
| 3:00 - 4:30 | Special Session II: Research Idea Exchange (speed-dating style) |
Day 5 – June 19
| Session Chair: Rohit Bhargava | |
| 9:00 - 9:50 | The Chemical and Mechanical Signals Driving Neutrophil Polarity and Chemotaxis Fei Wang (Illinois) |
| 9:50 - 10:40 | New Soft Materials for Wound Repair and Tissue Engineering Paul Janmey (U Penn) |
| 10:40 - 11:00 | Coffee break |
| 11:00 - 11:50 | Seeing the Unseen: the Force Story of a Cancer Cell Taher Saif (Illinois) |
| 11:50 - 12:50 | Lunch |
| 1:00 - 3:00 | Graduation Ceremony |
